Thursday, December 30, 2021

Procedure for Calibration of Balances in pharmaceutical industry

 MONTHLY CALIBRATION OF BALANCES 

For monthly Calibration of Balances check following parameters-

1. Accuracy - verify the balance with minimum weight (least count × 100), 5%, 20%, 50%, 90% capacity of respective balance capacity.

Tolerance - the variation if any should be ± least count of the balance or ± 0.2% of certified standard weight used whichever is higher 

 2. Reproducibility - 

Check the reproducibility by using minimum standard weight of balance capacity. Place the weight in the middle of the weighing pan observe the displayed value 

Then calculate the %RSD by following formula 

RSD= SD×100 / X 

Where, 

X= mean of the individual value

Acceptance = %RSD should not be more than 2.0%

3. Eccentricity 

Eccentricity is the difference between the weight placed in centre and at peripheral points of the weighing pan